Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition

Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition

Latent inhibition (LI) refers to the reduction in conditioning to a stimulus that has received repeated non-reinforced pre-exposure. Investigations into the neural substrates of LI have focused on the nucleus accumbens (NAc) and its inputs from the hippocampal formation and adjacent cortical areas. Previous work has suggested that lesions to the medial prefrontal cortex (mPFC), another major so...

Atecholaminergic Depletion within the Prelimbic Medial Refrontal Cortex Enhances Latent Inhibition

(2010) Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition. Neuroscience, 170 (1). pp. The Nottingham ePrints service makes this work by researchers of the University of Nottingham available open access under the following conditions. This article is made available under the Creative Commons Attribution licence and may be reused according to the ...

Behavioral Neuroscience The Effect of Catecholaminergic Depletion Within the Prelimbic and Infralimbic Medial Prefrontal Cortex on Recognition Memory for Recency, Location, and Objects

The Effect of Catecholaminergic Depletion Within the Prelimbic and Infralimbic Medial Prefrontal Cortex on Recognition Memory for Recency, Location, and Objects

There is good evidence that the medial prefrontal cortex (mPFC) is involved in different aspects of recognition memory. However, the mPFC is a heterogeneous structure, and the contribution of the prelimbic (PL) and infralimbic (IL) cortices to recognition memory has not been investigated. Similarly, the role of different neuromodulators within the mPFC in these processes is poorly understood. T...

prelimbic of medial prefrontal cortex GABA modulation through testosterone on spatial learning and memory

Prefrontal cortex (PFC) is involved in multiple functions including attentional , spatial orientation, short and long-term memory. Our previous study indicated that microinjection of testosterone in CA1 impaired spatial learning and memory. Some evidence suggests that impairment effect of testosterone is mediated by GABAergic system. In the present study, we investigated the interaction of test...